Lecture – 20 Nucleic Acids 1

Lecture Series on BioChemistry I by Prof.S.Dasgupta, Dept of Chemistry, IIT Kharagpur. For more details on NPTEl visit http://nptel.iitm.ac.in.
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eIF4A1 is a promising new therapeutic target in ER-negative breast cancer

eIF4A1 is a promising new therapeutic target in ER-negative breast cancer
Given the role of protein synthesis control in gene expression regulation, it is unsurprising that aberrant control of translation is associated with tumorigenesis.2 This can occur by enhanced signalling through to translation, releasing protein …
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Preparation of amino acid mixtures for cell-free expression systems
Here we present a procedure for preparing amino acid mixtures—having both the desired composition and a physiological pH—at high concentrations for cell-free expression systems. Up to 2.1 mg/mL of active protein was synthesized in batch mode …
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Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+
Methods: We generated a mouse with a Ca2+ binding and permeation defect in the voltage-dependent Ca2+ channel, CaV1.1, and used Ca2+ imaging, western blotting, immunohistochemistry, proximity ligation assays, SUnSET analysis of protein synthesis, …
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A Prescription For Better Teaching, Stronger Doctors

A Prescription For Better Teaching, Stronger Doctors
When I went to medical school, the first two years were classroom-based, where we learned everything from anatomy to physiology to biochemistry to embryology to genetics to neuroscience. … The problem is not lectures, but relying solely on lectures.
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M. Daniel Lane, Hopkins biochemist
"Every physician who trained at Johns Hopkins from 1970 until 2006, when he formally stopped teaching, remembers the 'Lane Lectures' in metabolism." Dr. Thomas August, a retired Hopkins scientist and colleague, said in an email, "He made numerous …
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High School Students Get Psyched About Science
Teachers, parents, and 520 students traveled from as far away as Cheyenne and as close as East High School to attend demonstrations and lectures given by faculty and staff from the College of Science. The five-hour event closed with a speech from the …
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Chinese Feed Additives Market Analysis and 2015 Forecasts in New Research Report at RnRMarketResearch.com

Dallas, Texas (PRWEB) August 02, 2013

Feed additives as upstream products of the feed industry refer to small (trace) amounts of nutritive or non-nutritive substances or drugs added to feed for specific needs. Its main role is to increase nutrient concentration and efficiency of feed utilization, promote livestock growth, prevent and cure diseases as well as reduce the loss of nutrients in feed.

In China, following the sustained and stable growth of feed industry, the feed additives industry has also made considerable progress. So far, there have been over 220 types of approved additives, including nearly 70 domestic types with standards, 57 types of allowed medicated additives. In 2011-2012, China’s additive premix remained between 6.1-6.4 million tons. By type, amino acids, vitamins, medicated additives and biological enzymes account for a high proportion of the feed additives market, up to 80% and more.

Get a copy of this report at http://www.rnrmarketresearch.com/china-feed-additives-industry-report-2012-2015-market-report.html.

With respect to the amino acid feed additives segment, as China gives priority to pig and poultry breeding, coupled with restricted level of feeding, the actual consumption structure of feed amino acids is oriented by methionine and lysine. In 2012, China’s lysine production and consumption were 855,000 tons and 610,000 tons, respectively, showing obvious overcapacity and fierce market competition. But limited by technical barriers, only one local enterprise – Chongqing Unisplendour Chemical Co., Ltd. had realized methionine industrialization by the end of 2012. In 2012, China consumed 194,000 tons of methionine, including imports of 183,000 tons.

Seen from the vitamin feed additives segment, China has become an important global feed vitamin producing and consuming country. In recent years, Chinese external exports of the vitamin have accounted for about 80% of the total output over the same period. In 2012, China produced 240,000 tons of vitamins, including exports of 187,000 tons. However, affected by the economic recession in Europe and America, the Chinese vitamin market in the future will face a grim situation, especially the export volume will fall even more. It is expected that Chinese vitamin production in 2013-2015 will be around 220,000-280,000 tons, with exports occupying 75%-80%.

In terms of the medicated additives segment, although Europe, the United States and other developed countries have already exercised strict control over the production and application of antibiotic drugs in feed, the proportion is still high in China. Feed-grade chlortetracycline (FG CTC) is one of them. In 2012 the world’s overall production capacity of FG CTC reached 100,000 tons/a, of which, China-based Jinhe Biotechnology Co., Ltd., Zhumadian Huazhong Chia Tai Co., Ltd and Pucheng Zhengda Biochemistry Co., Ltd. accounted for 85% or so.

China Feed Additives Industry Report, 2012-2015 of Research In China mainly includes the following aspects:

Development status, competition pattern, import & export and development trends of China feed additives industry;

Analysis on feed-use amino acids, vitamins, enzymes, medicated additives and other market segments;

Operation, feed additive business, development tendency, etc. of 14 domestic companies.

Purchase a copy of this report at http://www.rnrmarketresearch.com/contacts/purchase?rname=107071.

Browse more reports on Animal & Livestock Feed Market at http://www.rnrmarketresearch.com/reports/food-beverage/agriculture/animal-livestock-feed.

About Us:

RnRMarketResearch.com (http://www.rnrmarketresearch.com/.) is an online database of market research reports offers in-depth analysis of over 5000 market segments. The library has syndicated reports by leading market research publishers across the globe and also offer customized market research reports for multiple industries.







Neil Riordan, PhD to Present at the International Society for the Reversal of Chronic Diseases Symposium Organized by Shalesh Kaushal and Central Florida Health Alliance

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Lady Lake, FL (PRWEB) January 06, 2015

Neil Riordan, PhD, co-founder of the Riordan-McKenna Institute, will present “The Role of Mesenchymal Stem Cells in the Reversal of Chronic Diseases” this Saturday, January 10th at the International Society for the Reversal of Chronic Diseases’ inaugural symposium: “Can Chronic Diseases be Reversed?” in Lady Lake, Florida.

The symposium will run from 8 a.m. to 4 p.m. at the Harbor Chase Village Crossing assisted living facility on NE 86th Dr. in The Villages across from The Villages Regional Hospital in Lady Lake, Florida 32159. The facility of golf cart accessible and lunch will be served to all attendees.

Tickets are $ 10 per person and RSVP is requires. Attendance is limited to 100 participants.

For more information or to purchase tickets, please contact Sheri Tor at 352-323-5506 or email: stor(at)CFHAlliance(dot)org. Credit card payments are accepted.

Distinguished guests include:

Moderator: Shalesh Kaushal, MD, PhD: Retina Specialty Institute

BS: Yale University; MD: John Hopkins; PhD: MIT, with Nobel Laureate Dr. Har Gobind Khorana

Caldwell B. Esselstyn Jr., MD, Cleveland Clinic

Retired endocrine surgeon and author

He and Dr. Colin Campbell recommended a diet adopted by President Bill Clinton.

T. Colin Campbell, PhD, Cornell University

Jacob Gould Schurman Professor Emeritus of Nutritional Biochemistry

Thomas M. Campbell, MD, Rochester University

Executive director of the T. Colin Campbell Center for Nutrition Studies and Author

Arthur L. Horwich, MD, Yale University

Biologist and the Eugene Higgins Professor of Genetics and Pediatrics at Yale School of Medicine

Randy L. Jirtle, MD, Duke University (Retired)

Biologist known for his pioneering work in epigenetics and genomic imprinting.

2007 nominee for Time Person of the Year

Amir Lerman, MD, Mayo Clinic

Professor of Medicine, Division of Cardiovascular Diseases and Internal Medicine

Neil Riordan, PhD, Founder and Chairman, Medistem; Co-founder Riordan-McKenna Institute of Regenerative Orthopedics (RMI)

Medistem is a leading stem cell laboratory research facility at the forefront of the effects of adult stem cells for chronic diseases. RMI specializes in surgical and non-surgical regenerative orthopedics.

Alessio Fasano, MD, Harvard University

Director, Mass. General Hospital for Children Center for Celiac Research; Division Chief, Dept. of Pediatric Gastroenterology and Nutrition

Toren Finkel, MD, PhD, National Heart Lung and Blood Institute (NIH)

Research focuses on molecular mechanisms of aging and impact on the treatment of age-related diseases.

About Neil Riordan PhD

Neil H. Riordan, PhD is the co-founder and chief science officer of the Riordan-McKenna Institute (RMI) in Southlake, Texas. RMI specializes in surgical and non-surgical regenerative orthopedics. RMI’s Stemnexa™ protocols incorporate the latest scientific advances in bone marrow harvesting, bone marrow aspirate concentration of stem cells and AlphaGEMS pliable tissue allograft.

Dr. Riordan is the founder and chairman of Medistem Panama, Inc., (MPI) a leading stem cell laboratory and research facility located in the Technology Park at the prestigious City of Knowledge in Panama City, Panama. Founded in 2007, MPI stands at the forefront of applied research on adult stem cells for several chronic diseases. MPI’s stem cell laboratory is ISO 9001 certified and fully licensed by the Panamanian Ministry of Health. Dr. Riordan is the founder of Stem Cell Institute (SCI) in Panama City, Panama (est. 2007).

Under the umbrella of MPI subsidiary Translational Biosciences, MPI and SCI are currently conducting five IRB-approved clinical trials in Panama for multiple sclerosis, rheumatoid arthritis and osteoarthritis using human umbilical cord-derived mesenchymal stem cells, mesenchymal trophic factors and stromal vascular fraction. Additional trials for spinal cord injury, autism and cerebral palsy are slated to commence in 2014 upon IRB approval.

Dr. Riordan is an accomplished inventor; listed on more the 25 patent families, including 11 issued patents. He is credited with a number of novel discoveries in the field of cancer research since the mid-1990s when he collaborated with his father Dr. Hugh Riordan on the effects of high-dose intravenous vitamin C on cancer cells and the tumor microenvironment. This pioneering study on vitamin C’s preferential toxicity to cancer cells notably led to a 1997 patent grant for the treatment of cancer with vitamin C. In 2010, Dr. Riordan received another patent for a new cellular cancer vaccine.

Dr. Riordan is also the founder of Aidan Products, which provides health care professionals with quality nutraceuticals including Stem-Kine, the only nutritional supplement that is clinically proven to increase the amount of circulating stem cells in the body for an extended period of time. Stem-Kine is currently sold in 35 countries.

Dr. Riordan earned his Bachelor of Science at Wichita State University and graduated magna cum laude. He received his Master’s degree at the University of Nebraska Medical Center. Dr. Riordan completed his education by earning a Ph.D. in Health Sciences at Medical University of the Americas.

About Riordan-McKenna Institute

Riordan-McKenna Institute is the only orthopedic clinic that combines proprietary biologic cellular therapies with state-of-the-art orthopedic interventions to postpone or eliminate the need for surgery, or augment a necessary surgery for faster healing and better patient outcomes.

RMI’s Stemnexa™ protocols incorporate the latest scientific advances in bone marrow harvesting, bone marrow aspirate concentration of stem cells and AlphaGEMS pliable tissue allograft to decrease healing time, increase vascularization, decrease pain, reduce inflammation, decrease infection rates, and increase safety.

Riordan-McKenna Institute

801 E. Southlake Blvd.

Southlake, TX 76092

Phone: (817) 776-8155

Toll Free: (877) 899-7836

Fax: (817) 776-8154

RMI Website: http://www.rmiclinic.com

About Stem Cell Institute Panama

Founded in 2007 on the principles of providing unbiased, scientifically sound treatment options; the Stem Cell Institute (SCI) has matured into the world’s leading adult stem cell therapy and research center. In close collaboration with universities and physicians world-wide, our comprehensive stem cell treatment protocols employ well-targeted combinations of autologous bone marrow stem cells, autologous adipose stem cells, and donor human umbilical cord stem cells to treat: multiple sclerosis, spinal cord injury, osteoarthritis, rheumatoid arthritis, heart disease, and autoimmune diseases.

In partnership with Translational Biosciences, a subsidiary of Medistem Panama, SCI provides clinical services for ongoing clinical trials that are assessing safety and signs of efficacy for osteoarthritis, rheumatoid arthritis, and multiple sclerosis using allogeneic umbilical cord tissue-derived mesenchymal stem cells (hUC-MSC), autologous stromal vascular fraction (SVF) and hU-MSC-derived mesenchymal trophic factors (MTF). In 2014, Translation Biosciences expects to expand its clinical trial portfolio to include spinal cord injury, heart disease, autism and cerebral palsy.

For more information on stem cell therapy:

Stem Cell Institute Website: http://www.cellmedicine.com

Stem Cell Institute

Via Israel & Calle 66

Plaza Pacific Office #2A

Panama City, Panama

About Medistem Panama Inc.

Since opening its doors in 2007, Medistem Panama Inc. has developed adult stem cell-based products from human umbilical cord tissue and blood, adipose (fat) tissue and bone marrow. Medistem operates an 8000 sq. ft. ISO 9001-certified laboratory in the prestigious City of Knowledge. The laboratory is fully licensed by the Panamanian Ministry of Health and features 3 class 10000 clean rooms, class 100 laminar flow hoods, and class 100 incubators.

Medistem Panama Inc.

Ciudad del Saber, Edif. 221 / Clayton

Panama, Rep. of Panama

Phone: +507 306-2601

Fax: +507 306-2601

Website: http://www.medistempanama.com

About Translational Biosciences

A subsidiary of Medistem Panama Inc., Translational Biosciences was founded solely to conduct clinical trials using adult stem cells and adult stem cell-derived products.

Translational Biosciences Web Site: http://www.translationalbiosciences.com







Synopsis | Elsevier’s Dictionary Of Chemistry: Including Terms From Biochemistry

BOOK REVIEW OF YOUR FAVORITE BOOK =— Where to buy this book? ISBN: 9780444422309 Book Review of Elsevier’s Dictionary of Chemistry: Including Terms fro…

Research of macroscopic with chemistry

 

Actual biochemistry is the research of macroscopic, nuclear, subatomic, and air particle phenomena in chemical type techniques with regards to physical regulations and ideas. It is applicable the concepts, methods and ideas of technology such as movement, power, power, time, thermodynamics, huge biochemistry, accurate aspects and characteristics.

Physical biochemistry assignment help

Physical biochemistry, as opposed to chemical type technology, is primarily (but not always) a macroscopic or supra-molecular technology, as many of the concepts on which physical biochemistry was established, are ideas relevant to the volume rather than on molecular/atomic framework alone. For example, chemical type stability, and colloids.

Some of the connections that physical biochemistry aims to take care of involve the results of:

Intermolecular makes that act upon the physical qualities of elements (plasticity, tensile durability, exterior stress in liquids).

Reaction kinetics on the amount of a response.

The identification of ions on the electric powered conductivity of elements.

Surface biochemistry and electrochemistry of membranes with chemistry assignment help

One of the key ideas in biochemistry is that all substances can be described as categories of atoms insured together and chemical type responses can be described as the making and splitting of those ties. Forecasting the qualities of substances from an information of atoms and how they rapport is one of the significant objectives of physical biochemistry.

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To explain the atoms and ties accurately, it is necessary to know both where the nuclei of the atoms are, and how electrons are allocated around them. Quantum biochemistry, a subfield of physical biochemistry especially worried with the use of huge aspects to chemical type problems, provides resources to figure out how powerful and what appearance ties are, how nuclei move, and how light can be consumed or produced by a chemical type substance. Spectroscopy is the relevant sub-discipline of physical biochemistry which is particularly worried with the relationship of radio waves with matter.

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Another set of important issues in biochemistry issues what kind of responses can occur in an instant and which qualities are possible for a given chemical type blend. This is examined in chemical type thermodynamics, which places restrictions on volumes like how far a response can continue, or how much power can be become work in a burning website and which provides hyperlinks between qualities like the heat development coefficient and change of amount in entropy with demand for a gas or a fluid.  It can regularly be used to figure out whether a reactor or website design is doable, or to check the credibility of fresh information. To a restricted level, quasi-equilibrium and non-equilibrium thermodynamics can explain permanent changes. However, traditional thermodynamics is mostly worried with techniques in stability and undoable changes and not what actually does occur, or how quick, away from stability.

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Which responses do occur and how quick is the topic of chemical type kinetics, another division of physical biochemistry. A key idea in chemical type kinetics is that for reactants to respond and form items, most chemical type types must go through move declares which are greater in power than either the reactants or the items and offer as a buffer to response. In common, the greater the buffer, the reduced the response. A second is that most chemical type responses occur as a series of middle responses, each with its own move state. Key issues in kinetics involve how the amount of response will depend on heat range and on the levels of reactants and causes in the response blend, as well as how causes and response circumstances can be designed to boost the response amount.

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The fact that how quick responses occur can often be specified with just a few levels and a heat range, instead of requiring to know all the opportunities and connections of every substance in a blend, is a special case of another key idea in physical biochemistry, which is that to the level an professional needs to know, everything going on in an assortment of an incredible number of huge of debris can often be described by just a few factors like demand, heat range, and attention. The accurate reasons for this are described in accurate aspects, a specialized within physical biochemistry which is also told technology. Statistical aspects also provide ways to estimate the qualities we see in life from molecular qualities without depending on test connections based on chemical type parallels.

 

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