Shift Workers Might Want to Skip High-Iron Foods at Night

Shift Workers Might Want to Skip High-Iron Foods at Night
When the clock in the liver gets out of synch with the one in the brain, it might contribute to metabolic diseases, according to Donald McClain, M.D., Ph.D., University of Utah professor of medicine (endocrinology) and biochemistry and senior author on …
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Structure of an iron-transport protein revealed
For the first time, the three dimensional structure of the protein that is essential for iron import into cells, has been elucidated. Biochemists of the University of Zurich have paved the way towards a better understanding of iron metabolism. The …
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Mussel-Based Protien Adhesives Could Change the Pasting Game
protein, mussel, adhesive Shellfish such as mussels and barnacles secrete very sticky proteins that help them cling to rocks or ship hulls, even underwater. Inspired by these natural adhesives, a team of MIT engineers has designed new materials that …
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The Long Battle Over Pesticides, Birth Defects and Mental Impairment

The Long Battle Over Pesticides, Birth Defects and Mental Impairment
These materials included Dow documents and correspondence, EPA documents, legal depositions, basic embryology, biochemistry and toxicology of chlorpyrifos, medical records of other exposed children, patents, books, articles, etc, etc. Chlorpyrifos was …
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Pitt Bucket List
“Earn a 4.0 semester.” — Mikalya Ferchaw, sophomore biochemistry major. “Get a job before I graduate.” — Suzy Hinkle … —Michael Watson, 2013 graduate, currently at University of Virginia for medical school. “Attend a big Pitt basketball game in …
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College partners with EVMS for physicians' assistant program
The College of William and Mary is expanding its partnership with Eastern Virginia Medical School with a new Early Assurance Program (EAP) for the EVMS Physician's Assistant program. Students receive prerequisite credits towards their application to …
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Mayo Clinic Releases Free Health App for iOS Devices

Mayo Clinic Releases Free Health App for iOS Devices
Apple's Health application is intended to be a personal and central data collection point for connected third-party electronic accessories and wearable technology that can directly monitor and analyze an individual's biochemistry and physiology for …
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Postdoctoral Fellow in Biochemistry / Antimicrobial Chemotherapy
Candidates must possess a Ph.D. in Biochemistry or a closely related field. The successful candidate will be expected to work on an NIH-funded project to test novel antibiotics against metallo-beta-lactamases, important antibiotic resistance factors …
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Meet students in WMU medical school's inaugural class as school prepares for
After high school he spent a year in community college, enlisted in the U.S. Air Force where he worked in nuclear debris collection and analysis, then he enrolled at Western Michigan University where he earned a bachelor's degree in biochemistry and a …
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Biochemistry: Why I Love my Major at Clemson University

Biochemistry major at Clemson University. “Why I Love my Major” Video Contest Submission (Video 6 of 10). To vote please visit: http://www.facebook.com/Clems…

Biochemists and Biophysicists Job Description

Biochemists and Biophysicists Job Description.

Lecture – 05 Protein Structure III

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Lecture - 05 Protein Structure III

Lecture Series on BioChemistry I by Prof.S.Dasgupta, Dept of Chemistry, IIT Kharagpur. For more details on NPTEl visit http://nptel.iitm.ac.in.

Site Specific ADC Generation Using SMARTag Technology Platform to be Presented at World ADC Congress

Somerset, N.J. (PRWEB) October 21, 2014

Dr. David Rabuka, Catalent Pharma Solutions’ Global Head of R&D Chemical Biology, is to present “Site Specific Antibody Drug Conjugate (ADC) Generation using SMARTag™ Technology” at the forthcoming World ADC Congress, which takes place from 26th to 29th October 2014, at the San Diego Marriott Marquis Hotel, San Diego, California.

Dr. Rabuka’s presentation, on Monday 27th October at 11 am, will explain how Catalent’s SMARTag technology platform enables precise and programmable site specific chemical protein modification and the development of novel conjugation chemistry resulting in ADCs with enhanced stability. He will also highlight specialized linker chemistry that optimizes the potency of the cytotoxic payload.

Catalent announced in October 2014 that it had purchased the remaining stake in SMARTag technology’s creator, Redwood Bioscience Inc., following the successful achievement of in vivo and in vitro proof of concept milestones, recent compelling in vivo toxicology data, and strong customer interest in the technology.

The novel, site-specific SMARTag technology enables the generation of homogenous bioconjugates, engineered to improve performance and ease of manufacturing. Combined with Catalent’s proprietary GPEx® cell line expression system, its new state-of-the-art biomanufacturing Center of Excellence in Madison, Wisconsin, and broad range of analytical and fill-finish services, Catalent helps its customers to develop more and better biologics treatments.

Dr. Rabuka assumed the role of Catalent Pharma Solutions’ Global Head of R&D Chemical Biology in October 2014, following Catalent’s acquisition of Redwood Bioscience Inc., where he had previously acted as President and Chief Scientific Officer. He received a Ph.D. in Chemistry at the University of California, Berkeley as a Chevron Fellow in the lab of Professor Carolyn Bertozzi. His research included developing and applying Redwood’s platform technology to cell surface modifications. Prior to joining Professor Bertozzi’s lab, Dr. Rabuka worked at the Burnham Institute, synthesizing complex glycans, followed by Optimer Pharmaceuticals, where he was an early employee, focused on the development of glycan and macrolide based antibiotics. He graduated with a double honors B.S. in Chemistry and Biochemistry from the University of Saskatchewan where he received the Dean’s Science Award and holds an M.S. in Chemistry from the University of Alberta. Dr. Rabuka is an author on over 20 major publications, as well as numerous book chapters and patents.

About Catalent

Catalent Pharma Solutions, is the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products. With over 80 years serving the industry, Catalent has proven expertise in bringing more customer products to market faster, enhancing product performance and ensuring reliable clinical and commercial product supply. Catalent employs approximately 8,000 people, including over 1,000 scientists, at nearly 30 facilities across 5 continents and in fiscal 2014 generated more than $ 1.8 billion in annual revenue. Catalent is headquartered in Somerset, N.J. For more information, visit http://www.catalent.com

More products. Better treatments. Reliably supplied.™